Development of progressive kidney damage and myeloma kidney in interleukin-6 transgenic mice
نویسندگان
چکیده
منابع مشابه
Development of progressive kidney damage and myeloma kidney in interleukin-6 transgenic mice.
Interleukin-6 (IL-6) is a pleiotropic cytokine that has been postulated as playing a role in the pathogenesis of multiple myeloma, chronic autoimmune diseases, and alcoholic liver cirrhosis. We generated transgenic mice carrying a fusion between the mouse metallothionein-I (MT-I) gene promoter and the human IL-6 cDNA. MT-I/IL-6 transgenics express IL-6 constitutively in the liver and secrete th...
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ژورنال
عنوان ژورنال: Blood
سال: 1994
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v83.9.2570.bloodjournal8392570